Likely to cause
Can cause
May cause
DIISODECYL PHTHALATE (DIDP) (alternate CASRN is 68515-49-1)
CAS: 26761-40-0
How can this chemical affect my health?
Acute (Short Term) Effects
Data sources
Chronic (Long Term) Effects

Birth Defects – Harm to the developing child including birth defects, low birth weight and biological or behavioral problems that appear as the child grows.

Endocrine Disruption – Interference with the endocrine system, which plays a crucial role in metabolism, development, growth, reproduction and behavior.

Reproductive Harm – Disruption of the male or female reproductive systems, changing sexual development, behavior or functions, decreasing fertility, or resulting in loss of the fetus during pregnancy.

Cancer – Increased cancer risk.

Allergen/Asthmagen – Immune system responses that result in respiratory health effects that occur with increased sensitivity to lower and lower exposures over time.
Data sources
Direct Hazard » Birth Defects
These sources refer directly to this chemical:
- Developmental toxicityCA EPA - Prop 65California Environmental Protection Agency (CA EPA)
- Clear Evidence of Adverse Effects - Developmental ToxicityUS NIH - Reproductive & Developmental MonographsUS Department of Health & Human Services - National Institutes of Health (US NIH)
- Developmental toxicity - TSCA Criteria metUS EPA - PPT Chemical Action PlansUS Environmental Protection Agency (US EPA)
Direct Hazard » Endocrine Disruption
These sources refer directly to this chemical:
- Category 2 - In vitro evidence of biological activity related to Endocrine DisruptionEU - Priority Endocrine DisruptorsEuropean Union / European Commission (EU EC)
- Endocrine DisruptionChemSec - SIN ListChemSec, The International Chemical Secretariat
- Potential Endocrine DisruptorTEDX - Potential Endocrine DisruptorsThe Endocrine Disruption Exchange (TEDX)
- UNEP EDCsUNEP EDCsUnited Nations Environment Programme (UNEP)
Direct Hazard » Reproductive Harm
These sources refer directly to this chemical:
- Some Evidence of no Adverse Effects - Reproductive ToxicityUS NIH - Reproductive & Developmental MonographsUS Department of Health & Human Services - National Institutes of Health (US NIH)
- Reproductive effectsUS EPA - PPT Chemical Action PlansUS Environmental Protection Agency (US EPA)
- H361 - Suspected of damaging fertility or the unborn child [Toxic to reproduction - Category 2]GHS - JapanGovernment of Japan
Direct Hazard » Cancer
These sources refer directly to this chemical:
- Carcinogen Group 3B - Evidence of carcinogenic effects but not sufficient for classificationMAKMAK Commission of Germany (Deutsche Forschungsgemeinschaft)
Phthalates (orthophthalates) » Allergen/Asthmagen
These sources refer to a group of compounds containing this chemical:
- Asthma - allergen, sensitizer - limited evidenceCHE - Toxicant DatabaseCollaborative on Health and the Environment (CHE)
- Asthma - irritant - limited evidenceCHE - Toxicant DatabaseCollaborative on Health and the Environment (CHE)
- Rhinitis – allergic - limited evidenceCHE - Toxicant DatabaseCollaborative on Health and the Environment (CHE)
Inherent Hazards

Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.
Data sources
Direct Hazard » Restricted List
These sources refer directly to this chemical:
- EPA Chemical of Concern - Action Plan publishedUS EPA - PPT Chemical Action PlansUS Environmental Protection Agency (US EPA)
- TSCA Work Plan chemical - Action Plan in developmentUS EPA - PPT Chemical Action PlansUS Environmental Protection Agency (US EPA)
- Precautionary list of substances recommended for avoidanceP&W - Precautionary ListPerkins+Will (P+W)
- TSCA Work Plan chemical - ongoing chemical (risk) assessmentUS EPA - PPT Chemical Action PlansUS Environmental Protection Agency (US EPA)
- Chemicals of high concernSCHF - Hazardous 100Toxic-Free Future (formerly Safer Chemicals, Healthy Families (SCHF))
- Priority Asthmagen to AvoidHabitable - Priority AsthmagensHabitable (formerly HBN)
- Candidate Chemical ListCA SCP - Candidate ChemicalsCalifornia Department of Toxic Substance Control (CA DTSC)
- Red List substances to avoid in Living Building Challenge V3 projectsLiving Building Challenge 3.0 - Red List of Materials & Chemicals (retiring December 31, 2024)International Living Future Institute (ILFI)
- Assessment of regulatory needsEU - PACT-RMOA SubstancesEuropean Union / European Commission (EU EC)
- V3 2014 Substance of Concern ListBIFMA - e3/level Annex B list of chemicalsBusiness and Institutional Furniture Manufacturers Association (BIFMA)
- Bisphenols and PhthalatesGSPI - Six Classes Precautionary ListGreen Science Policy Institute (GSPI)
- Some SolventsGSPI - Six Classes Precautionary ListGreen Science Policy Institute (GSPI)
- Substances restricted under REACHEU - REACH Annex XVII non-CMRsEuropean Union / European Commission (EU EC)
- Chemicals of High ConcernMDH - Chemicals of High Concern and Priority ChemicalsMinnesota Department of Public Health
- Chemicals of High Concern to ChildrenWA DoE - Chemicals of High Concern to ChildrenWashington State Department of Ecology (WA DOE)
- Designated ChemicalCA DTSC - Biomonitoring California Chemical ListCalifornia Department of Toxic Substance Control (CA DTSC)
- CoHC List (non SVHC)CPA - Chemical FootprintClean Production Action (CPA)
- Children's ProductsC2C Certified v4.0 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022Cradle to Cradle Products Innovation Institute (C2CPII)
- ZDHC - MRSL v1.1 for Textiles and Synthetic Leather ProcessingZDHC - MRSL v1.1Zero Discharge of Hazardous Waste Chemicals Programme
- ZDHC - MRSL v1.1 for Natural Leather ProcessingZDHC - MRSL v1.1Zero Discharge of Hazardous Waste Chemicals Programme
- Red List substances to avoid in Living Building Challenge V3.1 projectsLiving Building Challenge 3.1 - Red List of Materials & Chemicals (retiring December 31, 2024)International Living Future Institute (ILFI)
- Red List substances to avoid in Living Building Challenge V4.0 projectsLiving Building Challenge 4.0 - Red List of Materials & Chemicals - Effective February 1, 2025International Living Future Institute (ILFI)
- 2019 Substance of Concern ListBIFMA - e3/level Annex B list of chemicalsBusiness and Institutional Furniture Manufacturers Association (BIFMA)
- Tier 1 “Do Not Use Chemicals” for EveryoneCampaign for Safe Cosmetics’ Red List of Chemicals of ConcernCampaign for Safe Cosmetics
- Declarable and Reference Substance Lists (DSL and RSL)IEC 62474 - Material Declaration for Products of and for the Electrotechnical IndustryInternational Electrotechnical Commission
- Chemicals of High Concern to ChildrenVermont Chemicals of High Concern to ChildrenVermont Environmental Health Division
- Food Contact Chemicals of Concern List (FCCoCL) - TIER 1Food Contact Chemicals of Concern (FCCoCL)Food Packaging Forum
- PhthalatesAmerican Apparel and Footwear Association Restricted Substance List (AAFA RSL)American Apparel and Footwear Association
- Target Priority Chemicals List (TPCL)Target Corp - Target Priority Chemicals List (TPCL)Target Corporation
- ZDHC - MRSL v2.0ZDHC - MRSL v2.0Zero Discharge of Hazardous Waste Chemicals Programme
- EDF Key chemicals of concern in food packaging and food handling equipmentEDF Key chemicals of concern in food packaging and food handling equipmentEnvironmental Defense Fund
- FSAP Food Packaging Product Stewardship ConsiderationsFSAP Food Packaging Product Stewardship ConsiderationsFood Safety Alliance for Packaging (FSAP)
- FPF Priority Substance List from FCCdbFPF Priority Substance List from FCCdbFood Packaging Forum
- Ortho-PhthalatesGreenScreen Certified Standard for Food Service Ware RSLClean Production Action (CPA)
- Food Packaging Forum Priority Substances ListGreenScreen Certified Standard for Food Service Ware RSLClean Production Action (CPA)
- PhthalatesAFIRM Packaging RSL v8 (2025)The Apparel and Footwear International RSL Management Group (AFIRM)
- Ortho-phthalates (Bronze List)GreenScreen Certified Standard for Furniture & Fabrics Bronze RSLClean Production Action (CPA)
- Ortho-phthalates (Silver-Gold)GreenScreen Certified Standard for Furniture & Fabrics Silver-Gold RSLClean Production Action (CPA)
- ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0GreenScreen Certified Standard for Furniture & Fabrics Silver-Gold RSLClean Production Action (CPA)
- ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0GreenScreen Certified Standard for Firefighting Foam RSLClean Production Action (CPA)
- ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0GreenScreen Certified Standard for Textile Chemicals RSLClean Production Action (CPA)
- GADSL Declarable Substances - Information is being collected for a non-regulatory purpose (D/FI)Global Automotive Declarable Substance List (GADSL)Global Automotive Stakeholder Group (GASG)
- Ortho-phthalates (Silver-Gold)GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSLClean Production Action (CPA)
- ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSLClean Production Action (CPA)
- GreenScreen LT-1 (based on 2018 Chemical Footprint Project)GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSLClean Production Action (CPA)
- Ortho-Phthalates (Bronze)GreenScreen Certified Standard for Medical Supplies & Devices Bronze RSLClean Production Action (CPA)
- Potential CHRONIC health effects (over time or long-term)OR OHA - High Priority Chemicals of Concern for Children's Health (HPCCCH)Oregon Health Authority
- Restricted Substances in ProductsApple Regulated Substances SpecificationApple Inc.
- Reportable Substances and Future Restrictions in ProductsApple Regulated Substances SpecificationApple Inc.
- TSCA - Substantial Risk NoticesTSCA Chemical Substantial Risk NoticesUS Environmental Protection Agency (US EPA)
- All ProductsC2C Certified v4.1 Product Standard Restricted Substances - Effective July 1, 2025Cradle to Cradle Products Innovation Institute (C2CPII)
- Trade Union Priority List 2.0ETUC - Trade Union Priority List 2.0European Trade Union Confederation (ETUC)
- CSCP - Reportable Ingredient ListCalifornia Safe Cosmetics Program - Reportable Ingredient ListCalifornia Department of Public Health (CDPH)
- ZDHC - MRSL v3.1ZDHC - MRSL v3.1Zero Discharge of Hazardous Waste Chemicals Programme
- PhthalatesAFIRM RSL v10 (2025)The Apparel and Footwear International RSL Management Group (AFIRM)
- OEKO-TEX STANDARD 100OEKO-TEX® STANDARD 100International Association for Research and Testing in the Field of Textile and Leather Ecology (OEKO-TEX)
Phthalates (orthophthalates) » Restricted List
These sources refer to a group of compounds containing this chemical:
- Red List substance to avoid in Living Building Challenge V2.1 projectsLiving Building Challenge 2.1 - Red List of Materials & Chemicals (retired in 2014)International Living Future Institute (ILFI)
- Substance to avoid to fulfill LEED Pilot Credit 11USGBC - LEED Pilot CreditsUS Green Building Council (USGBC)
- Substance to avoid to fulfill LEED Pilot Credit 54 Option 2USGBC - LEED Pilot CreditsUS Green Building Council (USGBC)
- Priority ChemicalsME DEP - Chemicals of High Concern and Priority ChemicalsMaine Department of Environmental Protection
- Prospective Red List substances to avoid in Living Building Challenge projectsLiving Building Challenge 3.0 - Red List of Materials & Chemicals (retiring December 31, 2024)International Living Future Institute (ILFI)
- Prohibited ChemicalsCredo Beauty's Restricted Substance ListCredo
- Priority ChemicalsMind the Store Priority Chemical Classes & GroupsToxic-Free Future (formerly Safer Chemicals, Healthy Families (SCHF))
- OrthophthalatesBora's Chemicals of Concern ListBora Architecture & Interiors
- WA TFCAWA DoE Toxic-Free Cosmetics Act (TFCA)Washington State Department of Ecology (WA DOE)
Ortho-phthalates - Biomonitoring Ca » Restricted List
These sources refer to a group of compounds containing this chemical:
- Priority ChemicalCA DTSC - Biomonitoring California Chemical ListCalifornia Department of Toxic Substance Control (CA DTSC)
[68515-49-1] Diisodecyl Phthalate (didp) (primary Casrn Is 26761-40-0) » Restricted List
These sources refer to a group of compounds containing this chemical:
- Food Contact Chemicals of Concern List (FCCoCL) - TIER 2Food Contact Chemicals of Concern (FCCoCL)Food Packaging Forum
- Data generation and assessmentEU - PACT-RMOA SubstancesEuropean Union / European Commission (EU EC)
How does this chemical impact the environment?

Chronic Harm to Aquatic Ecosystems – Irreversible harm to fish or other aquatic organisms following long term exposure.
Data sources
Direct Hazard » Chronic Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H413 - May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment (chronic) - Category 4]GHS - JapanGovernment of Japan
What safer alternatives are available for this chemical?
Information on safer alternatives is currently fairly limited, and not easily accessible or linked to information on chemicals in the workplace. Where we have information on safer alternatives, ChemHAT will display links to existing case studies of safer alternatives for the chemical.