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Key to Symbols
ChemHAT health impact icons have different colors depending on the strength of the evidence. For example, when authoritative government bodies have definitively determined that a chemical can cause cancer in people, the icon will be red to show that it is the strongest evidence base.




PBT (Persistent Bioaccumulative Toxicant) – Harm in small quantities while not breaking down readily from natural processes, accumulating in organisms, and concentrating as it moves up the food chain.

Cancer – Increased cancer risk.

Breast Cancer – Increased risk of mammary gland tumors in animal experiments.

Birth Defects – Harm to the developing child including birth defects, low birth weight and biological or behavioral problems that appear as the child grows.

Reproductive Harm – Disruption of the male or female reproductive systems, changing sexual development, behavior or functions, decreasing fertility, or resulting in loss of the fetus during pregnancy.

Endocrine Disruption – Interference with the endocrine system, which plays a crucial role in metabolism, development, growth, reproduction and behavior.

Gene Damage – Increases in the rate of mutations, which are changes in genetic material in cells.

Allergen/Asthmagen – Immune system responses that result in respiratory health effects that occur with increased sensitivity to lower and lower exposures over time.

Brain/Nervous System Harm – Damage to the nervous system including the brain.

Toxic to Humans & Animals – Toxicity or fatality on contact, ingestion or inhalation to humans and other mammals.

Other Health Effects – Can cause serious damage on contact or ingestion.

Eye Irritation – Irritation or serious damage to the eyes.

Skin Irritation – Irritation or serious damage to the skin.

Skin Sensitization – Allergic skin reactions.

Flammable – Easily ignited and capable of burning rapidly.

Reactive – May spontaneously ignite or explode on its own or in contact with water.

Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Acute Harm to Aquatic Ecosystems – Biological harm or possible death to fish or other aquatic organisms following a single exposure.

Chronic Harm to Aquatic Ecosystems – Irreversible harm to fish or other aquatic organisms following long term exposure.

Harm to Land Ecosystems – Harm to land based plants, animals or microorganisms.

Climate Change – Climate change by contributing to the greenhouse effect or trapping heat in the atmosphere.

Ozone Depletion – Chemical reactions that destroy ozone in the earth’s upper atmosphere allowing cancer-causing ultraviolet radiation from the sun to hit our skin.

Persistent – Does not break down readily from natural processes.

Bio-accumulation – Accumulation in organisms, concentrating as it moves up the food chain.