Stronger effect / evidence




Weaker effect / evidence
Stoddard solvent
CAS: 8052-41-3
How can this chemical affect my health?
Acute (Short Term) EffectsData sources

Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.

Irritates the Skin – Can cause irritation or serious damage to the skin.

Irritates the Eyes – Can cause irritation or serious damage to the eye.
Data sources
Direct Hazard » Toxic to Humans & Animals
These sources refer directly to this chemical:
- FIFRA Registered PesticideUS EPA - OPP - Registered PesticidesUS Environmental Protection Agency (US EPA)
- H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]GHS - JapanGovernment of Japan
- H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H304 - May be fatal if swallowed and enters airways [Aspiration hazard - Category 1]GHS - AustraliaSafe Work Australia
- H302 - Harmful if swallowed (unverified) [Acute toxicity (oral) - Category 4]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H304 - May be fatal if swallowed and enters airways (unverified) [Aspiration hazard - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H331 - Toxic if inhaled (unverified) [Acute toxicity (inhalation) - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Irritates the Skin
These sources refer directly to this chemical:
- H315 - Causes skin irritation [Skin corrosion / irritation - Category 2]GHS - JapanGovernment of Japan
- H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Irritates the Eyes
These sources refer directly to this chemical:
- H319 - Causes serious eye irritation (unverified) [Serious eye damage/eye irritation - Category 2A]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Chronic (Long Term) EffectsData sources

Gene Damage – Can cause or increase the rate of mutations, which are changes in genetic material in cells.

Cancer – Can cause or increase the risk of cancer.

Other Health Effects – Can cause serious damage on contact or ingestion.

Brain/Nervous System Harm – Can cause damage to the nervous system including the brain.
Data sources
Direct Hazard » Gene Damage
These sources refer directly to this chemical:
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Germ cell mutagens: Category 1BEU - REACH Annex XVII CMRsEuropean Union / European Commission (EU EC)
- Mutagen - Category 1BEU - Annex VI CMRsEuropean Union / European Commission (EU EC)
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]GHS - AustraliaSafe Work Australia
- H340 - May cause genetic defects (unverified) [Germ cell mutagenicity - Category 1A or 1B]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Cancer
These sources refer directly to this chemical:
- H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Carcinogens: Category 1BEU - REACH Annex XVII CMRsEuropean Union / European Commission (EU EC)
- Carcinogen Category 1B - Presumed Carcinogen based on animal evidenceEU - Annex VI CMRsEuropean Union / European Commission (EU EC)
- H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]GHS - AustraliaSafe Work Australia
- H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Other Health Effects
These sources refer directly to this chemical:
- H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H373 - May cause damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 2]GHS - JapanGovernment of Japan
- H335 or H336 [Specific target organs/systemic toxicity following single exposure - Category 3]GHS - JapanGovernment of Japan
- H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]GHS - AustraliaSafe Work Australia
- H335 - May cause respiratory irritation (unverified) [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Brain/Nervous System Harm
These sources refer directly to this chemical:
- NeurotoxicBoyes - NeurotoxicantsPattys Toxicology: author William K Boyes
- H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Inherent HazardsData sources

Flammable – Easily ignited and capable of burning rapidly.

Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.
Data sources
Direct Hazard » Flammable
These sources refer directly to this chemical:
- Class B3 - Combustible liquidsQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
- H226 - Flammable liquid and vapour (unverified) [Flammable liquids - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H225 - Highly flammable liquid and vapour (unverified) [Flammable liquids - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Restricted List
These sources refer directly to this chemical:
- Candidate Chemical ListCA SCP - Candidate ChemicalsCalifornia Department of Toxic Substance Control (CA DTSC)
- Substances selected for RMOA or hazard assessmentEU - PACT-RMOA SubstancesEuropean Union / European Commission (EU EC)
- Some SolventsGSPI - Six Classes of Problematic ChemicalsGreen Science Policy Institute (GSPI)
- Chemicals of High ConcernMDH - Chemicals of High Concern and Priority ChemicalsMinnesota Department of Public Health
- CoHC List (non SVHC)CPA - Chemical FootprintClean Production Action (CPA)
- Formulated Consumer ProductsC2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022Cradle to Cradle Products Innovation Institute (C2CPII)
- Food Contact Chemicals Database Version 5.0Food Contact Chemicals Database (FCCdb)Food Packaging Forum
- Food Contact Chemicals of Concern List (FCCoCL) - TIER 3Food Contact Chemicals of Concern (FCCoCL)Food Packaging Forum
- Substances of Very High Concern (RIVM ZZS)Substances of Very High Concern (RIVM ZZS)The National Institute for Public Health and the Environment (RIVM)
- FPF Priority Substance List from FCCdbFPF Priority Substance List from FCCdbFood Packaging Forum
- Food Packaging Forum Priority Substances ListGreenScreen Certified Standard for Food Service Ware RSLClean Production Action (CPA)
- TSCA Chemical Substance Inventory - ActiveTSCA Chemical Substance Inventory (Active-Inactive)US Environmental Protection Agency (US EPA)
- GreenScreen List Translator LT-1GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSLClean Production Action (CPA)
How does this chemical impact the environment?Data sources

Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.

Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.

Bioaccumulative – Accumulates in organisms, concentrating as it moves up the food chain.
Data sources
Direct Hazard » Immediate Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]GHS - JapanGovernment of Japan
Direct Hazard » Long-Term Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H410 - Very toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 1]GHS - JapanGovernment of Japan
- H412 - Harmful to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H411 - Toxic to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Bioaccumulative
These sources refer directly to this chemical:
- BioaccumulativeEC - CEPA DSLEnvironment Canada & Health Canada (EC)
What safer alternatives are available for this chemical?
Find case studies related to substitutions for this chemical in SubsPORT, the substitution support portal.