Stronger effect / evidence
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Weaker effect / evidence

Stoddard solvent

CAS: 8052-41-3

How can this chemical affect my health?

Acute (Short Term) EffectsData sources

Toxic To Humans & Animals, priority yellow
Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.
Irritates The Skin, priority orange
Irritates the Skin – Can cause irritation or serious damage to the skin.
Irritates The Eyes, priority gray
Irritates the Eyes – Can cause irritation or serious damage to the eye.

Chronic (Long Term) EffectsData sources

Gene Damage, priority red
Gene Damage – Can cause or increase the rate of mutations, which are changes in genetic material in cells.
Cancer, priority red
Cancer – Can cause or increase the risk of cancer.
Other Health Effects, priority orange
Other Health Effects – Can cause serious damage on contact or ingestion.
Brain/nervous System Harm, priority gray
Brain/Nervous System Harm – Can cause damage to the nervous system including the brain.

Data sources

Direct Hazard » Gene Damage

These sources refer directly to this chemical:

  • H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • Germ cell mutagens: Category 1B
    EU - REACH Annex XVII CMRs
    European Union / European Commission (EU EC)
  • Mutagen - Category 1B
    EU - Annex VI CMRs
    European Union / European Commission (EU EC)
  • H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
    GHS - Malaysia
    Malaysia Department of Occupational Safety and Health
  • H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]
    GHS - Australia
    Safe Work Australia
  • H340 - May cause genetic defects (unverified) [Germ cell mutagenicity - Category 1A or 1B]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Cancer

These sources refer directly to this chemical:

  • H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • Carcinogens: Category 1B
    EU - REACH Annex XVII CMRs
    European Union / European Commission (EU EC)
  • Carcinogen Category 1B - Presumed Carcinogen based on animal evidence
    EU - Annex VI CMRs
    European Union / European Commission (EU EC)
  • H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
    GHS - Malaysia
    Malaysia Department of Occupational Safety and Health
  • H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
    GHS - Australia
    Safe Work Australia
  • H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Other Health Effects

These sources refer directly to this chemical:

  • H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • H373 - May cause damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 2]
    GHS - Japan
    Government of Japan
  • H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
    GHS - Australia
    Safe Work Australia
  • H335 - May cause respiratory irritation (unverified) [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H335 - May cause respiratory irritation [Specific target organ toxicity - Single exposure - Category 3]
    GHS - Japan
    Government of Japan

Direct Hazard » Brain/Nervous System Harm

These sources refer directly to this chemical:

  • Neurotoxic
    Boyes - Neurotoxicants
    Pattys Toxicology: author William K Boyes
  • H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
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Inherent HazardsData sources

Flammable, priority yellow
Flammable – Easily ignited and capable of burning rapidly.
Restricted List, priority gray
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Data sources

Direct Hazard » Flammable

These sources refer directly to this chemical:

  • Class B3 - Combustible liquids
    Québec CSST - WHMIS 1988
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
  • H226 - Flammable liquid and vapour (unverified) [Flammable liquids - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H225 - Highly flammable liquid and vapour (unverified) [Flammable liquids - Category 2]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Restricted List

These sources refer directly to this chemical:

  • Candidate Chemical List
    CA SCP - Candidate Chemicals
    California Department of Toxic Substance Control (CA DTSC)
  • Substances selected for RMOA or hazard assessment
    EU - PACT-RMOA Substances
    European Union / European Commission (EU EC)
  • Some Solvents
    GSPI - Six Classes Precautionary List
    Green Science Policy Institute (GSPI)
  • Chemicals of High Concern
    MDH - Chemicals of High Concern and Priority Chemicals
    Minnesota Department of Public Health
  • CoHC List (non SVHC)
    CPA - Chemical Footprint
    Clean Production Action (CPA)
  • Children's Products
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • Formulated Consumer Products
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • Food Contact Chemicals Database Version 5.0
    Food Contact Chemicals Database (FCCdb)
    Food Packaging Forum
  • Food Contact Chemicals of Concern List (FCCoCL) - TIER 3
    Food Contact Chemicals of Concern (FCCoCL)
    Food Packaging Forum
  • Substances of Very High Concern (RIVM ZZS)
    Substances of Very High Concern (RIVM ZZS)
    The National Institute for Public Health and the Environment (RIVM)
  • FPF Priority Substance List from FCCdb
    FPF Priority Substance List from FCCdb
    Food Packaging Forum
  • Food Packaging Forum Priority Substances List
    GreenScreen Certified Standard for Food Service Ware RSL
    Clean Production Action (CPA)
  • TSCA Chemical Substance Inventory - Active
    TSCA Chemical Substance Inventory (Active-Inactive)
    US Environmental Protection Agency (US EPA)
  • GreenScreen LT-1 (based on 2018 Chemical Footprint Project)
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)
  • Restricted Substances in Products
    Apple Regulated Substances Specification
    Apple Inc.
  • DSL-all
    EC - CEPA DSL
    Environment Canada & Health Canada (EC)

Halogenated Solvents » Restricted List

These sources refer to a group of compounds containing this chemical:

  • Core Restrictions
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • Limit standard for volatile organic compounds content in adhesives (GB 33372-2020)
    China's limit standard for volatile organic compounds
    State Administration for Market Regulation - Standardization Administration of China
  • Limit standard for volatile organic compounds content in printing inks (GB 38507-2020)
    China's limit standard for volatile organic compounds
    State Administration for Market Regulation - Standardization Administration of China

Halogenated Organic Compounds » Restricted List

These sources refer to a group of compounds containing this chemical:

  • Organohalogens (including chlorinated plastics)
    GreenScreen Certified Standard for Food Service Ware RSL
    Clean Production Action (CPA)
  • Organohalogens
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)
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How does this chemical impact the environment?Data sources

Immediate Harm To Aquatic Ecosystems, priority orange
Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.
Long-term Harm To Aquatic Ecosystems, priority orange
Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.
Bioaccumulative , priority red
Bioaccumulative – Accumulates in organisms, concentrating as it moves up the food chain.

Data sources

Direct Hazard » Immediate Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]
    GHS - Japan
    Government of Japan

Direct Hazard » Long-Term Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H410 - Very toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 1]
    GHS - Japan
    Government of Japan
  • H412 - Harmful to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H411 - Toxic to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 2]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Bioaccumulative

These sources refer directly to this chemical:

  • Bioaccumulative
    EC - CEPA DSL
    Environment Canada & Health Canada (EC)
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What safer alternatives are available for this chemical?

Find case studies related to substitutions for this chemical in SubsPORT, the substitution support portal.