Ethylene oxide
How can this chemical affect my health?
Acute (Short Term) EffectsData sources
Data sources
Direct Hazard » Toxic to Humans & Animals
These sources refer directly to this chemical:
- FIFRA Registered PesticideUS EPA - OPP - Registered PesticidesUS Environmental Protection Agency (US EPA)
- H301 - Toxic if swallowed [Acute toxicity (oral) - Category 3]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H331 - Toxic if inhaled [Acute toxicity (inhalation) - Category 3]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Extremely Hazardous SubstancesUS EPA - EPCRA Extremely Hazardous SubstancesUS Environmental Protection Agency (US EPA)
- H331 - Toxic if inhaled [Acute toxicity (inhalation) - Category 3]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- H301 - Toxic if swallowed [Acute toxicity (oral) - Category 3]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- Class D1A - Very toxic material causing immediate and serious toxic effectsQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
- H331 - Toxic if inhaled [Acute toxicity (inhalation: gas) - Category 3]GHS - JapanGovernment of Japan
- H301 - Toxic if swallowed [Acute Toxicity (oral) - Category 3]GHS - JapanGovernment of Japan
- H331 - Toxic if inhaled [Acute toxicity (inhalation) - Category 3]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]GHS - AustraliaSafe Work Australia
- H331 - Toxic if inhaled [Acute toxicity (inhalation) - Category 3]GHS - AustraliaSafe Work Australia
- H302 - Harmful if swallowed (unverified) [Acute toxicity (oral) - Category 4]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H301 - Toxic if swallowed (unverified) [Acute toxicity (oral) - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H331 - Toxic if inhaled (unverified) [Acute toxicity (inhalation) - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H330 - Fatal if inhaled (unverified) [Acute toxicity (inhalation) - Category 1 or 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Acute inhalation toxicity category 3GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- Acute oral toxicity category 3GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
Direct Hazard » Irritates the Skin
These sources refer directly to this chemical:
- H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- Skin irritation category 2GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H315 - Causes skin irritation [Skin corrosion / irritation - Category 2]GHS - JapanGovernment of Japan
- H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]GHS - AustraliaSafe Work Australia
- H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H314 - Causes severe skin burns and eye damage (unverified) [Skin corrosion/irritation - Category 1A or 1B or 1C]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Irritates the Eyes
These sources refer directly to this chemical:
- H318 - Causes serious eye damage [Serious eye damage/eye irritation - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H319 - Causes serious eye irritation [Serious eye damage/irritation - Category 2]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- Eye irritation category 2GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H319 - Causes serious eye irritation [Serious eye damage / eye irritation - Category 2A]GHS - JapanGovernment of Japan
- H319 - Causes serious eye irritation [Serious eye damage/eye irritation - Category 2A]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H319 - Causes serious eye irritation (unverified) [Serious eye damage/eye irritation - Category 2A]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H318 - Causes serious eye damage (unverified) [Serious eye damage/eye irritation - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Chronic (Long Term) EffectsData sources
Data sources
Direct Hazard » Asthma Trigger
These sources refer directly to this chemical:
- Asthmagen (A) - expert listed pending AEOC reviewAOEC - AsthmagensAssociation of Occupational and Environmental Clinics (AOEC)
- Asthmagen (Rr) - irritant-inducedAOEC - AsthmagensAssociation of Occupational and Environmental Clinics (AOEC)
- Respiratory sensitisation category 1GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- Asthma - allergen, sensitizer - good evidenceCHE - Toxicant DatabaseCollaborative on Health and the Environment (CHE)
- Agent Causing Occupational AsthmaQuebec CSST - Asthma AgentsQuébec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
Direct Hazard » Brain/Nervous System Harm
These sources refer directly to this chemical:
- NeurotoxicG&L - Neurotoxic ChemicalsLancet: authors Philippe Grandjean & Phil Landrigan
- H336 - May cause drowsiness or dizziness [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Cancer
These sources refer directly to this chemical:
- (1999, 2005) Carcinogenic to humansUS EPA - IRIS CarcinogensUS Environmental Protection Agency (US EPA)
- Group 1 - Agent is Carcinogenic to humansIARCInternational Agency for Research on Cancer, World Health Organization (IARC)
- CarcinogenCA EPA - Prop 65California Environmental Protection Agency (CA EPA)
- Occupational CarcinogenUS CDC - Occupational CarcinogensUS Centers for Disease Control (US CDC)
- Known to be a human CarcinogenUS NIH - Report on CarcinogensUS Department of Health & Human Services - National Institutes of Health (US NIH)
- H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Carcinogens: Category 1BEU - REACH Annex XVII CMRsEuropean Union / European Commission (EU EC)
- Carcinogen Group 2 - Considered to be carcinogenic for manMAKMAK Commission of Germany (Deutsche Forschungsgemeinschaft)
- H350 - May cause cancer [Carcinogenicity - Category 1]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- Carcinogen Category 1B - Presumed Carcinogen based on animal evidenceEU - Annex VI CMRsEuropean Union / European Commission (EU EC)
- Carcinogenicity category 1GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H350 - May cause cancer [Carcinogenicity - Category 1A]GHS - JapanGovernment of Japan
- H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]GHS - AustraliaSafe Work Australia
- H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Birth Defects
These sources refer directly to this chemical:
- Developmental toxicityCA EPA - Prop 65California Environmental Protection Agency (CA EPA)
Direct Hazard » Reproductive Harm
These sources refer directly to this chemical:
- Reproductive Toxicity - FemaleCA EPA - Prop 65California Environmental Protection Agency (CA EPA)
- Reproductive Toxicity - MaleCA EPA - Prop 65California Environmental Protection Agency (CA EPA)
- H360Fd - May damage fertility. Suspected of damaging the unborn child [Reproductive toxicity - Category 1A or 1B]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Reproductive toxicants: Category 1BEU - REACH Annex XVII CMRsEuropean Union / European Commission (EU EC)
- Reproductive toxicity category 1GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H360 - May damage fertility or the unborn child [Toxic to reproduction - Category 1B]GHS - JapanGovernment of Japan
- Reproductive Toxicity - Category 1BEU - Annex VI CMRsEuropean Union / European Commission (EU EC)
- H360 - Suspected of / May damage fertility and/or the unborn child (unverified) [Reproductive toxicity - Category 1A or 1B]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Other Health Effects
These sources refer directly to this chemical:
- H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H335 - May cause respiratory irritation [Specific target organ toxicity - Single exposure - Category 3]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]GHS - JapanGovernment of Japan
- H373 - May cause damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 2]GHS - JapanGovernment of Japan
- H370 - Causes damage to organs [Specific target organs/systemic toxicity following single exposure - Category 1]GHS - JapanGovernment of Japan
- H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]GHS - AustraliaSafe Work Australia
- H335 - May cause respiratory irritation (unverified) [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H335 - May cause respiratory irritation [Specific target organ toxicity - Single exposure - Category 3]GHS - JapanGovernment of Japan
- Specific target organ toxicity - repeated exposure category 1GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
Direct Hazard » Gene Damage
These sources refer directly to this chemical:
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Germ cell mutagens: Category 1BEU - REACH Annex XVII CMRsEuropean Union / European Commission (EU EC)
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- Mutagen - Category 1BEU - Annex VI CMRsEuropean Union / European Commission (EU EC)
- Germ cell mutagenicity category 1GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1B]GHS - JapanGovernment of Japan
- Germ Cell Mutagen 2MAKMAK Commission of Germany (Deutsche Forschungsgemeinschaft)
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H340 - May cause genetic defects [Germ cell mutagenicity - Category 1A or 1B]GHS - AustraliaSafe Work Australia
- H340 - May cause genetic defects (unverified) [Germ cell mutagenicity - Category 1A or 1B]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Endocrine Disruption
These sources refer directly to this chemical:
- Potential Endocrine DisruptorTEDX - Potential Endocrine DisruptorsThe Endocrine Disruption Exchange (TEDX)
- ECHA Endocrine disruptor assessment listECHA Endocrine DisruptorsEuropean Chemicals Agency (ECHA)
Direct Hazard » Breast Cancer
These sources refer directly to this chemical:
- Chemicals that increased mammary gland tumors in animal studiesSilent Spring - Breast Cancer ChemicalsSilent Spring Institute
Direct Hazard » Sensitizes the Skin
These sources refer directly to this chemical:
- Skin sensitisation category 1GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H317 - May cause an allergic skin reaction [Skin sensitizer - Category 1]GHS - JapanGovernment of Japan
- H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]GHS - AustraliaSafe Work Australia
Inherent HazardsData sources
Data sources
Direct Hazard » Restricted List
These sources refer directly to this chemical:
- Cancer causing substances subject to workplace management or avoidanceUS OSHA - CarcinogensUS Department of Labor
- HAPs subject to the Clean Air ActUS EPA - Hazardous Air PollutantsUS Environmental Protection Agency (US EPA)
- Annex III Restricted PesticideUNEP - PIC Annex IIIUnited Nations Environment Programme (UNEP)
- Candidate Chemical ListCA SCP - Candidate ChemicalsCalifornia Department of Toxic Substance Control (CA DTSC)
- Substances selected for RMOA or hazard assessmentEU - PACT-RMOA SubstancesEuropean Union / European Commission (EU EC)
- V3 2014 Substance of Concern ListBIFMA - e3/level Annex B list of chemicalsBusiness and Institutional Furniture Manufacturers Association (BIFMA)
- AntimicrobialsGSPI - Six Classes Precautionary ListGreen Science Policy Institute (GSPI)
- Ingredients that are Prohibited for Use in Cosmetic ProductsHealth Canada - Cosmetic Ingredient HotlistHealth Canada
- Chemicals of High ConcernMDH - Chemicals of High Concern and Priority ChemicalsMinnesota Department of Public Health
- Annex II - Prohibited SubstancesEU - Cosmetics RegulationEuropean Union / European Commission (EU EC)
- CoHC List (non SVHC)CPA - Chemical FootprintClean Production Action (CPA)
- Children's ProductsC2C Certified v4.0 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022Cradle to Cradle Products Innovation Institute (C2CPII)
- Formulated Consumer ProductsC2C Certified v4.0 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022Cradle to Cradle Products Innovation Institute (C2CPII)
- 2019 Substance of Concern ListBIFMA - e3/level Annex B list of chemicalsBusiness and Institutional Furniture Manufacturers Association (BIFMA)
- Tier 1 “Do Not Use Chemicals” for EveryoneCampaign for Safe Cosmetics’ Red List of Chemicals of ConcernCampaign for Safe Cosmetics
- Prohibited ChemicalsCredo Beauty's Restricted Substance ListCredo
- Reportable ChemicalsMA Toxics Use Reduction Act (TURA) listed substancesMassachusetts Department of Environmental Protection
- Cosmetics & Personal Care ProductsC2C Certified v4.0 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022Cradle to Cradle Products Innovation Institute (C2CPII)
- Food Contact Chemicals Database Version 5.0Food Contact Chemicals Database (FCCdb)Food Packaging Forum
- Food Contact Chemicals of Concern List (FCCoCL) - TIER 2Food Contact Chemicals of Concern (FCCoCL)Food Packaging Forum
- Substances of Very High Concern (RIVM ZZS)Substances of Very High Concern (RIVM ZZS)The National Institute for Public Health and the Environment (RIVM)
- FSAP Food Packaging Product Stewardship ConsiderationsFSAP Food Packaging Product Stewardship ConsiderationsFood Safety Alliance for Packaging (FSAP)
- FPF Priority Substance List from FCCdbFPF Priority Substance List from FCCdbFood Packaging Forum
- Other Chemicals of ConcernGreenScreen Certified Standard for Food Service Ware RSLClean Production Action (CPA)
- Food Packaging Forum Priority Substances ListGreenScreen Certified Standard for Food Service Ware RSLClean Production Action (CPA)
- TSCA Commercially ActiveTSCA Chemical Substance Inventory (Active-Inactive)US Environmental Protection Agency (US EPA)
- GreenScreen LT-1 (based on 2018 Chemical Footprint Project)GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSLClean Production Action (CPA)
- Tier 1 “Do Not Use” Chemicals of Greater Concern for Black WomenCampaign for Safe Cosmetics’ Red List of Chemicals of ConcernCampaign for Safe Cosmetics
- Restricted Substances in ProductsApple Regulated Substances SpecificationApple Inc.
- Reportable Substances and Future Restrictions in ProductsApple Regulated Substances SpecificationApple Inc.
- DSL-allEC - CEPA DSLEnvironment Canada & Health Canada (EC)
- TSCA - Substantial Risk NoticesTSCA Chemical Substantial Risk NoticesUS Environmental Protection Agency (US EPA)
- NICNASAustralia - National Industrial Chemicals Notification and Assessments (NICNAS)Australian Government
- All ProductsC2C Certified v4.1 Product Standard Restricted Substances - Effective July 1, 2024Cradle to Cradle Products Innovation Institute (C2CPII)
- Cosmetics and Personal Care ProductsC2C Certified v4.1 Product Standard Restricted Substances - Effective July 1, 2024Cradle to Cradle Products Innovation Institute (C2CPII)
- Japan - CSCLJapan - Chemical Substances Control LawGovernment of Japan
Direct Hazard » Flammable
These sources refer directly to this chemical:
- H220 - Extremely flammable gas [Flammable gases - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H220 - Extremely flammable gas [Flammable gases - Category 1]GHS - KoreaRepublic of Korea - National Institute of Environmental Research (NIER)
- Class B1 - Flammable gasesQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
- H220 - Extremely flammable gas [Flammable gases - Category 1]GHS - JapanGovernment of Japan
- H220 - Extremely flammable gas [Flammable gases - Category 1]GHS - MalaysiaMalaysia Department of Occupational Safety and Health
- H220 - Extremely flammable gas [Flammable gases - Category 1]GHS - AustraliaSafe Work Australia
- H220 - Extremely flammable gas (unverified) [Flammable gases - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Flammable gas category 1A, chemically unstable gas AGHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
Direct Hazard » Reactive
These sources refer directly to this chemical:
- Class E - Corrosive materialsQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
- Class F - Dangerously reactive materialsQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
How does this chemical impact the environment?Data sources
Data sources
Direct Hazard » Persistent
These sources refer directly to this chemical:
- PersistentEC - CEPA DSLEnvironment Canada & Health Canada (EC)
Direct Hazard » Immediate Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H402 - Harmful to aquatic life [Hazardous to the aquatic environment (acute) - Category 3]GHS - JapanGovernment of Japan