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Dibutyltin dilaurate

CAS: 77-58-7

How can this chemical affect my health?

Acute (Short Term) EffectsData sources

Toxic To Humans & Animals, priority gray
Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.
Irritates The Skin, priority yellow
Irritates the Skin – Can cause irritation or serious damage to the skin.
Irritates The Eyes, priority yellow
Irritates the Eyes – Can cause irritation or serious damage to the eye.

Chronic (Long Term) EffectsData sources

Asthma Trigger, priority yellow
Asthma Trigger – Can result in high sensitivity so that small quantities trigger asthma, nose or sinus inflammation or other allergic reactions in the respiratory system.
Reproductive Harm, priority red
Reproductive Harm – Can disrupt the male or female reproductive systems, changing sexual development, behavior or functions, decreasing fertility, or resulting in loss of the fetus during pregnancy.
Endocrine Disruption, priority orange
Endocrine Disruption – Can interfere with hormone communication between cells which controls metabolism, development, growth, reproduction and behavior (the endocrine system).
Cancer, priority orange
Cancer – Can cause or increase the risk of cancer.
Birth Defects, priority red
Birth Defects – Can cause harm to the developing child including birth defects, low birth weight and biological or behavioral problems that appear as the child grows.
Other Health Effects, priority orange
Other Health Effects – Can cause serious damage on contact or ingestion.
Gene Damage, priority orange
Gene Damage – Can cause or increase the rate of mutations, which are changes in genetic material in cells.
Sensitizes The Skin, priority gray
Sensitizes the Skin – Can lead to allergic reactions on the skin.

Data sources

Organotin Compounds » Asthma Trigger

These sources refer to a group of compounds containing this chemical:

  • Suspected asthmagen (R) - but does not meet AOEC criteria)
    AOEC - Asthmagens
    Association of Occupational and Environmental Clinics (AOEC)

Direct Hazard » Reproductive Harm

These sources refer directly to this chemical:

  • Toxic to Reproduction Category 2 - Substances which should be regarded as if they impair fertility or cause Developmental Toxicity in humans
    EU - REACH Annex XVII CMRs
    European Union / European Commission (EU EC)
  • H360 - May damage fertility or the unborn child [Toxic to reproduction - Category 1B]
    GHS - Japan
    Government of Japan
  • Reproductive Toxicity - Category 1B
    EU - Annex VI CMRs
    European Union / European Commission (EU EC)
  • H360FD - May damage fertility. May damage the unborn child [Reproductive toxicity - Category 1A or 1B]
    GHS - Australia
    Safe Work Australia
  • H360 - Suspected of / May damage fertility and/or the unborn child (unverified) [Reproductive toxicity - Category 1A or 1B]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Endocrine Disruption

These sources refer directly to this chemical:

  • Endocrine Disruption
    ChemSec - SIN List
    ChemSec, The International Chemical Secretariat
  • Potential Endocrine Disruptor
    TEDX - Potential Endocrine Disruptors
    The Endocrine Disruption Exchange (TEDX)

Direct Hazard » Other Health Effects

These sources refer directly to this chemical:

  • H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]
    GHS - Japan
    Government of Japan
  • H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
    GHS - Australia
    Safe Work Australia
  • H335 - May cause respiratory irritation (unverified) [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H373 - May cause damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 2]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H370 - Causes damage to organs (unverified) [Specific target organ toxicity - single exposure - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • Specific target organ toxicity - repeated exposure category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Gene Damage

These sources refer directly to this chemical:

  • H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
    GHS - Australia
    Safe Work Australia
  • H341 - Suspected of causing genetic defects (unverified) [Germ cell mutagenicity - Category 2]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Sensitizes the Skin

These sources refer directly to this chemical:

  • H317 - May cause an allergic skin reaction (unverified) [Skin sensitization - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Asthma Trigger

These sources refer directly to this chemical:

  • H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled (unverified) [Respiratory sensitization - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Dibutyltin Compounds » Cancer

These sources refer to a group of compounds containing this chemical:

  • Carcinogen Group 4 - Non-genotoxic carcinogen with low risk under MAK/BAT levels
    MAK
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)

Dibutyltin Compounds » Birth Defects

These sources refer to a group of compounds containing this chemical:

  • Pregnancy Risk Group B
    MAK
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)
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Inherent HazardsData sources

Restricted List, priority gray
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Data sources

Direct Hazard » Restricted List

These sources refer directly to this chemical:

  • Precautionary list of substances recommended for avoidance
    P&W - Precautionary List
    Perkins+Will (P+W)
  • Candidate Chemical List
    CA SCP - Candidate Chemicals
    California Department of Toxic Substance Control (CA DTSC)
  • Substances selected for RMOA or hazard assessment
    EU - PACT-RMOA Substances
    European Union / European Commission (EU EC)
  • Some Solvents
    GSPI - Six Classes of Problematic Chemicals
    Green Science Policy Institute (GSPI)
  • Annex II - Prohibited Substances
    EU - Cosmetics Regulation
    European Union / European Commission (EU EC)
  • Formulated Consumer Products
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • Watch List Substances Considered for Inclusion in the Living Building Challenge Red List
    Living Building Challenge 4.0 - Red List of Materials & Chemicals - Effective April 1, 2022
    International Living Future Institute (ILFI)
  • Declarable and Reference Substance Lists (DSL and RSL)
    IEC 62474 - Material Declaration for Products of and for the Electrotechnical Industry
    International Electrotechnical Commission
  • Food Contact Chemicals Database Version 5.0
    Food Contact Chemicals Database (FCCdb)
    Food Packaging Forum
  • Food Contact Chemicals of Concern List (FCCoCL)
    Food Contact Chemicals of Concern (FCCoCL)
    Food Packaging Forum
  • Food Contact Chemicals of Concern List (FCCoCL) - TIER 3
    Food Contact Chemicals of Concern (FCCoCL)
    Food Packaging Forum
  • Substances of Very High Concern (RIVM ZZS)
    Substances of Very High Concern (RIVM ZZS)
    The National Institute for Public Health and the Environment (RIVM)
  • ZDHC - MRSL v2.0
    ZDHC - MRSL v2.0
    Zero Discharge of Hazardous Waste Chemicals Programme
  • FPF Priority Substance List from FCCdb
    FPF Priority Substance List from FCCdb
    Food Packaging Forum
  • Food Packaging Forum Priority Substances List
    GreenScreen Certified Standard for Food Service Ware RSL
    Clean Production Action (CPA)
  • TSCA Chemical Substance Inventory - Active
    TSCA Chemical Substance Inventory (Active-Inactive)
    US Environmental Protection Agency (US EPA)
  • Metals and their Compounds (non-Electronic): Cadmium, Lead, Mercury, Organotin, and Antimony
    GreenScreen Certified Standard for Furniture & Fabrics Bronze RSL
    Clean Production Action (CPA)
  • ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0
    GreenScreen Certified Standard for Furniture & Fabrics Silver-Gold RSL
    Clean Production Action (CPA)
  • Metals and their Compounds (non-Electronic): Cadmium, Lead, Mercury, Organotin, and Antimony
    GreenScreen Certified Standard for Furniture & Fabrics Silver-Gold RSL
    Clean Production Action (CPA)
  • ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0
    GreenScreen Certified Standard for Firefighting Foam RSL
    Clean Production Action (CPA)
  • ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0
    GreenScreen Certified Standard for Textile Chemicals RSL
    Clean Production Action (CPA)
  • Metals and their Compounds (non-Electronic)
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)
  • ZDHC Manufacturing Restricted Substances List (MRSL) Version 2.0
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)
  • Metals and their Compounds (non-Electronic)
    GreenScreen Certified Standard for Medical Supplies & Devices Bronze RSL
    Clean Production Action (CPA)
  • GreenScreen List Translator LT-1
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)

Organotin Compounds » Restricted List

These sources refer to a group of compounds containing this chemical:

  • Chemicals of high concern
    SCHF - Hazardous 100
    Safer Chemicals, Healthy Families (SCHF)
  • Substances restricted under REACH
    EU - REACH Annex XVII non-CMRs
    European Union / European Commission (EU EC)
  • CoHC List (non SVHC)
    CPA - Chemical Footprint
    Clean Production Action (CPA)
  • Biological and Environmentally Released Materials
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • Children's Products
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • Persistent, Bioaccumulative, and Toxic Chemicals (PBTs)
    GreenScreen Certified Standard for Furniture & Fabrics Bronze RSL
    Clean Production Action (CPA)
  • Persistent, Bioaccumulative, and Toxic Chemicals (PBTs)
    GreenScreen Certified Standard for Furniture & Fabrics Silver-Gold RSL
    Clean Production Action (CPA)
  • Persistent, Bioaccumulative, and Toxic Chemicals (PBTs)
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)
  • Persistent, Bioaccumulative, and Toxic Chemicals (PBTs)
    GreenScreen Certified Standard for Medical Supplies & Devices Bronze RSL
    Clean Production Action (CPA)

Dibutyltin Compounds » Restricted List

These sources refer to a group of compounds containing this chemical:

  • Core Restrictions
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • ZDHC - MRSL v1.1 for Textiles and Synthetic Leather Processing
    ZDHC - MRSL v1.1
    Zero Discharge of Hazardous Waste Chemicals Programme
  • ZDHC - MRSL v1.1 for Natural Leather Processing
    ZDHC - MRSL v1.1
    Zero Discharge of Hazardous Waste Chemicals Programme
  • Organotin Compounds
    GreenScreen Certified Standard for Food Service Ware RSL
    Clean Production Action (CPA)
  • Organotin Compounds
    AFIRM Packaging RSL
    The Apparel and Footwear International RSL Management Group (AFIRM)
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How does this chemical impact the environment?Data sources

Immediate Harm To Aquatic Ecosystems, priority orange
Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.
Long-term Harm To Aquatic Ecosystems, priority orange
Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.

Data sources

Direct Hazard » Immediate Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]
    GHS - Japan
    Government of Japan
  • H400 - Very toxic to aquatic life (unverified) [Hazardous to the aquatic environment (acute) - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • Hazardous to the aquatic environment - acute category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Long-Term Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H410 - Very toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 1]
    GHS - Japan
    Government of Japan
  • H410 - Very toxic to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H411 - Toxic to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 2]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • Hazardous to the aquatic environment - chronic category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
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What safer alternatives are available for this chemical?

Information on safer alternatives is currently fairly limited, and not easily accessible or linked to information on chemicals in the workplace. Where we have information on safer alternatives, ChemHAT will display links to existing case studies of safer alternatives for the chemical.