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Weaker effect / evidence

Chlorine dioxide

CAS: 10049-04-4

How can this chemical affect my health?

Acute (Short Term) EffectsData sources

Toxic To Humans & Animals, priority yellow
Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.
Irritates The Skin, priority orange
Irritates the Skin – Can cause irritation or serious damage to the skin.
Irritates The Eyes, priority orange
Irritates the Eyes – Can cause irritation or serious damage to the eye.

Chronic (Long Term) EffectsData sources

Cancer, priority gray
Cancer – Can cause or increase the risk of cancer.
Endocrine Disruption, priority orange
Endocrine Disruption – Can interfere with hormone communication between cells which controls metabolism, development, growth, reproduction and behavior (the endocrine system).
Birth Defects, priority gray
Birth Defects – Can cause harm to the developing child including birth defects, low birth weight and biological or behavioral problems that appear as the child grows.
Reproductive Harm, priority red
Reproductive Harm – Can disrupt the male or female reproductive systems, changing sexual development, behavior or functions, decreasing fertility, or resulting in loss of the fetus during pregnancy.
Other Health Effects, priority orange
Other Health Effects – Can cause serious damage on contact or ingestion.

Data sources

Direct Hazard » Cancer

These sources refer directly to this chemical:

  • (1996) Carcinogenic potential cannot be determined
    US EPA - IRIS Carcinogens
    US Environmental Protection Agency (US EPA)
  • (1986) Group D - Not classifiable as to human carcinogenicity
    US EPA - IRIS Carcinogens
    US Environmental Protection Agency (US EPA)

Direct Hazard » Endocrine Disruption

These sources refer directly to this chemical:

  • Potential Endocrine Disruptor
    TEDX - Potential Endocrine Disruptors
    The Endocrine Disruption Exchange (TEDX)

Direct Hazard » Birth Defects

These sources refer directly to this chemical:

  • Pregnancy Risk Group D
    MAK
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)

Direct Hazard » Reproductive Harm

These sources refer directly to this chemical:

  • H360 - May damage fertility or the unborn child [Toxic to reproduction - Category 1A]
    GHS - Japan
    Government of Japan
  • H360 - May damage fertility or the unborn child [Toxic to reproduction - Category 1B]
    GHS - Japan
    Government of Japan

Direct Hazard » Other Health Effects

These sources refer directly to this chemical:

  • H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]
    GHS - Japan
    Government of Japan
  • H370 - Causes damage to organs [Specific target organs/systemic toxicity following single exposure - Category 1]
    GHS - Japan
    Government of Japan
  • Specific target organ toxicity - repeated exposure category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
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Inherent HazardsData sources

Reactive, priority orange
Reactive – May spontaneously ignite or explode on its own or in contact with water.
Restricted List, priority gray
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Data sources

Direct Hazard » Reactive

These sources refer directly to this chemical:

  • H270 - May cause or intensify fire; oxidiser (GAS ONLY) [Oxidizing gases - Category 1]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • Class C - Oxidizing materials
    Québec CSST - WHMIS 1988
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
  • Class E - Corrosive materials
    Québec CSST - WHMIS 1988
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
  • Class F - Dangerously reactive materials
    Québec CSST - WHMIS 1988
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
  • Oxidising gases category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
  • H270 - May cause or intensify fire; oxidizer [Oxidizing gases - Category 1]
    GHS - Korea
    Republic of Korea - National Institute of Environmental Research (NIER)
  • H270 - May cause or intensify fire; oxidiser (GAS ONLY) [Oxidizing gases - Category 1]
    GHS - Australia
    Safe Work Australia

Direct Hazard » Restricted List

These sources refer directly to this chemical:

  • Candidate Chemical List
    CA SCP - Candidate Chemicals
    California Department of Toxic Substance Control (CA DTSC)
  • Antimicrobials
    GSPI - Six Classes of Problematic Chemicals
    Green Science Policy Institute (GSPI)
  • Chemicals of High Concern
    MDH - Chemicals of High Concern and Priority Chemicals
    Minnesota Department of Public Health
  • Reportable Chemicals
    MA Toxics Use Reduction Act (TURA) listed substances
    Massachusetts Department of Environmental Protection
  • Food Contact Chemicals Database Version 5.0
    Food Contact Chemicals Database (FCCdb)
    Food Packaging Forum
  • Food Contact Chemicals of Concern List (FCCoCL) - TIER 3
    Food Contact Chemicals of Concern (FCCoCL)
    Food Packaging Forum
  • FPF Priority Substance List from FCCdb
    FPF Priority Substance List from FCCdb
    Food Packaging Forum
  • Food Packaging Forum Priority Substances List
    GreenScreen Certified Standard for Food Service Ware RSL
    Clean Production Action (CPA)
  • TSCA Chemical Substance Inventory - Active
    TSCA Chemical Substance Inventory (Active-Inactive)
    US Environmental Protection Agency (US EPA)
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How does this chemical impact the environment?Data sources

Immediate Harm To Aquatic Ecosystems, priority orange
Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.
Long-term Harm To Aquatic Ecosystems, priority orange
Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.
Harmful To Land Ecosystems, priority red
Harmful to Land Ecosystems – Can cause harm to land based plants, animals or microorganisms.

Data sources

Direct Hazard » Immediate Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]
    GHS - Korea
    Republic of Korea - National Institute of Environmental Research (NIER)
  • H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]
    GHS - Japan
    Government of Japan
  • H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]
    GHS - Australia
    Safe Work Australia
  • Hazardous to the aquatic environment - acute category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Long-Term Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H410 - Very toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 1]
    GHS - Japan
    Government of Japan
  • Hazardous to the aquatic environment - chronic category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Harmful to Land Ecosystems

These sources refer directly to this chemical:

  • Hazardous to soil organisms
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
  • Hazardous to terrestrial vertebrates
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
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What safer alternatives are available for this chemical?

Information on safer alternatives is currently fairly limited, and not easily accessible or linked to information on chemicals in the workplace. Where we have information on safer alternatives, ChemHAT will display links to existing case studies of safer alternatives for the chemical.

How am I likely to be exposed to this chemical?

Toxic if swallowed
Ingestion
Causes severe skin burns and eye damage
Skin contact
Fatal if inhaled
Inhalation

How can I protect myself from exposure to this chemical in the workplace?

gloves
Handle with gloves
suit
Protective clothing
respirator
Respirator