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2-Butanone oxime

CAS: 96-29-7

How can this chemical affect my health?

Acute (Short Term) EffectsData sources

Toxic To Humans & Animals, priority yellow
Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.
Irritates The Skin, priority yellow
Irritates the Skin – Can cause irritation or serious damage to the skin.
Irritates The Eyes, priority orange
Irritates the Eyes – Can cause irritation or serious damage to the eye.

Chronic (Long Term) EffectsData sources

Sensitizes The Skin, priority yellow
Sensitizes the Skin – Can lead to allergic reactions on the skin.
Brain/nervous System Harm, priority yellow
Brain/Nervous System Harm – Can cause damage to the nervous system including the brain.
Cancer, priority red
Cancer – Can cause or increase the risk of cancer.
Other Health Effects, priority orange
Other Health Effects – Can cause serious damage on contact or ingestion.
Asthma Trigger, priority gray
Asthma Trigger – Can result in high sensitivity so that small quantities trigger asthma, nose or sinus inflammation or other allergic reactions in the respiratory system.

Data sources

Direct Hazard » Sensitizes the Skin

These sources refer directly to this chemical:

  • H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • Sensitizing Substance Sh - Danger of skin sensitization
    MAK
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)
  • Skin sensitisation category 1
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
  • H317 - May cause an allergic skin reaction [Skin sensitizer - Category 1]
    GHS - Japan
    Government of Japan
  • H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]
    GHS - Australia
    Safe Work Australia
  • H317 - May cause an allergic skin reaction (unverified) [Skin sensitization - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Brain/Nervous System Harm

These sources refer directly to this chemical:

  • H336 - May cause drowsiness or dizziness [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Cancer

These sources refer directly to this chemical:

  • H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • Carcinogens: Category 1B
    EU - REACH Annex XVII CMRs
    European Union / European Commission (EU EC)
  • Carcinogen Group 2 - Considered to be carcinogenic for man
    MAK
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)
  • Carcinogen Category 1B - Presumed Carcinogen based on animal evidence
    EU - Annex VI CMRs
    European Union / European Commission (EU EC)
  • Carcinogenicity category 2
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
  • H351 - Suspected of causing cancer [Carcinogenicity - Category 2]
    GHS - Japan
    Government of Japan
  • H351 - Suspected of causing cancer [Carcinogenicity - Category 2]
    GHS - Australia
    Safe Work Australia
  • H351 - Suspected of causing cancer (unverified) [Carcinogenicity - Category 2]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Other Health Effects

These sources refer directly to this chemical:

  • H370 - Causes damage to organs [Specific target organ toxicity - single exposure - Category 1]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • H373 - May cause damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 2]
    EU - GHS (H-Statements) Annex 6 Table 3-1
    European Union / European Commission (EU EC)
  • H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]
    GHS - Japan
    Government of Japan
  • H373 - May cause damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 2]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • H370 - Causes damage to organs (unverified) [Specific target organ toxicity - single exposure - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • Specific target organ toxicity - repeated exposure category 2
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Asthma Trigger

These sources refer directly to this chemical:

  • H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled (unverified) [Respiratory sensitization - Category 1]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
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Inherent HazardsData sources

Flammable, priority yellow
Flammable – Easily ignited and capable of burning rapidly.
Restricted List, priority gray
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Data sources

Direct Hazard » Flammable

These sources refer directly to this chemical:

  • Flammable liquids category 3
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
  • H226 - Flammable liquid and vapour [Flammable liquids - Category 3]
    GHS - Japan
    Government of Japan
  • H226 - Flammable liquid and vapour (unverified) [Flammable liquids - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Restricted List

These sources refer directly to this chemical:

  • Candidate Chemical List
    CA SCP - Candidate Chemicals
    California Department of Toxic Substance Control (CA DTSC)
  • Substances selected for RMOA or hazard assessment
    EU - PACT-RMOA Substances
    European Union / European Commission (EU EC)
  • CoHC List (non SVHC)
    CPA - Chemical Footprint
    Clean Production Action (CPA)
  • Formulated Consumer Products
    C2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022
    Cradle to Cradle Products Innovation Institute (C2CPII)
  • Food Contact Chemicals Database Version 5.0
    Food Contact Chemicals Database (FCCdb)
    Food Packaging Forum
  • Substances of Very High Concern (RIVM ZZS)
    Substances of Very High Concern (RIVM ZZS)
    The National Institute for Public Health and the Environment (RIVM)
  • TSCA Chemical Substance Inventory - Active
    TSCA Chemical Substance Inventory (Active-Inactive)
    US Environmental Protection Agency (US EPA)
  • GreenScreen List Translator LT-1
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)
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How does this chemical impact the environment?Data sources

Persistent, priority red
Persistent – Does not break down readily from natural processes.
Immediate Harm To Aquatic Ecosystems, priority yellow
Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.
Long-term Harm To Aquatic Ecosystems, priority gray
Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.

Data sources

Direct Hazard » Persistent

These sources refer directly to this chemical:

  • Persistent
    EC - CEPA DSL
    Environment Canada & Health Canada (EC)

Direct Hazard » Immediate Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H402 - Harmful to aquatic life [Hazardous to the aquatic environment (acute) - Category 3]
    GHS - Japan
    Government of Japan

Direct Hazard » Long-Term Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H412 - Harmful to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 3]
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)
  • Hazardous to the aquatic environment - chronic category 3
    GHS - New Zealand
    New Zealand Environmental Protection Authority (NZ EPA)
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What safer alternatives are available for this chemical?

Find case studies related to substitutions for this chemical in SubsPORT, the substitution support portal.

How am I likely to be exposed to this chemical?

Toxic if swallowed
Ingestion
Harmful in contact with skin
Skin contact
Causes serious eye damage
Eye contact
May cause drowsiness or dizziness
Inhalation

How can I protect myself from exposure to this chemical in the workplace?

gloves
Handle with gloves
glasses
Safety eyeware
suit
Protective clothing
respirator
Respirator