Stronger effect / evidence
Weaker effect / evidence
2-Butanone oxime
CAS: 96-29-7
How can this chemical affect my health?
Acute (Short Term) EffectsData sources
Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.
Irritates the Skin – Can cause irritation or serious damage to the skin.
Irritates the Eyes – Can cause irritation or serious damage to the eye.
Data sources
Direct Hazard » Toxic to Humans & Animals
These sources refer directly to this chemical:
- H301 - Toxic if swallowed [Acute toxicity (oral) - Category 3]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H312 - Harmful in contact with skin [Acute toxicity (dermal) - Category 4]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H312 - Harmful in contact with skin [Acute Toxicity (dermal) - Category 4]GHS - JapanGovernment of Japan
- H302 - Harmful if swallowed [Acute Toxicity (oral) - Category 4]GHS - JapanGovernment of Japan
- H312 - Harmful in contact with skin [Acute toxicity (dermal) - Category 4]GHS - AustraliaSafe Work Australia
- H336 - May cause drowsiness or dizziness [Specific target organ toxicity - Single exposure - Category 3 (Narcotic effects)]GHS - JapanGovernment of Japan
- H312 - Harmful in contact with skin (unverified) [Acute toxicity (dermal) - Category 4]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H301 - Toxic if swallowed (unverified) [Acute toxicity (oral) - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Acute dermal toxicity category 4GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- Acute inhalation toxicity category 4GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- Acute oral toxicity category 4GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
Direct Hazard » Irritates the Skin
These sources refer directly to this chemical:
- H315 - Causes skin irritation [Skin corrosion/irritation - Category 2]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Irritates the Eyes
These sources refer directly to this chemical:
- H318 - Causes serious eye damage [Serious eye damage/eye irritation - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Eye irritation category 2GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H318 - Causes serious eye damage [Serious eye damage / eye irritation - Category 1]GHS - JapanGovernment of Japan
- H318 - Causes serious eye damage [Serious eye damage/eye irritation - Category 1]GHS - AustraliaSafe Work Australia
- H318 - Causes serious eye damage (unverified) [Serious eye damage/eye irritation - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Chronic (Long Term) EffectsData sources
Sensitizes the Skin – Can lead to allergic reactions on the skin.
Brain/Nervous System Harm – Can cause damage to the nervous system including the brain.
Cancer – Can cause or increase the risk of cancer.
Other Health Effects – Can cause serious damage on contact or ingestion.
Asthma Trigger – Can result in high sensitivity so that small quantities trigger asthma, nose or sinus inflammation or other allergic reactions in the respiratory system.
Data sources
Direct Hazard » Sensitizes the Skin
These sources refer directly to this chemical:
- H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Sensitizing Substance Sh - Danger of skin sensitizationMAKMAK Commission of Germany (Deutsche Forschungsgemeinschaft)
- Skin sensitisation category 1GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H317 - May cause an allergic skin reaction [Skin sensitizer - Category 1]GHS - JapanGovernment of Japan
- H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]GHS - AustraliaSafe Work Australia
- H317 - May cause an allergic skin reaction (unverified) [Skin sensitization - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Brain/Nervous System Harm
These sources refer directly to this chemical:
- H336 - May cause drowsiness or dizziness [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Cancer
These sources refer directly to this chemical:
- H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Carcinogens: Category 1BEU - REACH Annex XVII CMRsEuropean Union / European Commission (EU EC)
- Carcinogen Group 2 - Considered to be carcinogenic for manMAKMAK Commission of Germany (Deutsche Forschungsgemeinschaft)
- Carcinogen Category 1B - Presumed Carcinogen based on animal evidenceEU - Annex VI CMRsEuropean Union / European Commission (EU EC)
- Carcinogenicity category 2GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H350 - May cause cancer [Carcinogenicity - Category 1B]GHS - JapanGovernment of Japan
- H351 - Suspected of causing cancer [Carcinogenicity - Category 2]GHS - AustraliaSafe Work Australia
- H351 - Suspected of causing cancer (unverified) [Carcinogenicity - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Other Health Effects
These sources refer directly to this chemical:
- H370 - Causes damage to organs [Specific target organ toxicity - single exposure - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H373 - May cause damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 2]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]GHS - JapanGovernment of Japan
- H373 - May cause damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H370 - Causes damage to organs (unverified) [Specific target organ toxicity - single exposure - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Specific target organ toxicity - repeated exposure category 2GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
Direct Hazard » Asthma Trigger
These sources refer directly to this chemical:
- H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled (unverified) [Respiratory sensitization - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Inherent HazardsData sources
Flammable – Easily ignited and capable of burning rapidly.
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.
Data sources
Direct Hazard » Flammable
These sources refer directly to this chemical:
- Flammable liquids category 3GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
- H226 - Flammable liquid and vapour [Flammable liquids - Category 3]GHS - JapanGovernment of Japan
- H226 - Flammable liquid and vapour (unverified) [Flammable liquids - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Restricted List
These sources refer directly to this chemical:
- Candidate Chemical ListCA SCP - Candidate ChemicalsCalifornia Department of Toxic Substance Control (CA DTSC)
- Substances selected for RMOA or hazard assessmentEU - PACT-RMOA SubstancesEuropean Union / European Commission (EU EC)
- Annex II - Prohibited SubstancesEU - Cosmetics RegulationEuropean Union / European Commission (EU EC)
- CoHC List (non SVHC)CPA - Chemical FootprintClean Production Action (CPA)
- Children's ProductsC2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022Cradle to Cradle Products Innovation Institute (C2CPII)
- Formulated Consumer ProductsC2C Certified v4 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022Cradle to Cradle Products Innovation Institute (C2CPII)
- Food Contact Chemicals Database Version 5.0Food Contact Chemicals Database (FCCdb)Food Packaging Forum
- Substances of Very High Concern (RIVM ZZS)Substances of Very High Concern (RIVM ZZS)The National Institute for Public Health and the Environment (RIVM)
- TSCA Chemical Substance Inventory - ActiveTSCA Chemical Substance Inventory (Active-Inactive)US Environmental Protection Agency (US EPA)
- GreenScreen LT-1 (based on 2018 Chemical Footprint Project)GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSLClean Production Action (CPA)
- Restricted Substances in ProductsApple Regulated Substances SpecificationApple Inc.
- DSL-allEC - CEPA DSLEnvironment Canada & Health Canada (EC)
Skin Sensitising Substances - Apple Rss » Restricted List
These sources refer to a group of compounds containing this chemical:
- Reportable Substances and Future Restrictions in ProductsApple Regulated Substances SpecificationApple Inc.
How does this chemical impact the environment?Data sources
Persistent – Does not break down readily from natural processes.
Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.
Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.
Data sources
Direct Hazard » Persistent
These sources refer directly to this chemical:
- PersistentEC - CEPA DSLEnvironment Canada & Health Canada (EC)
Direct Hazard » Immediate Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H402 - Harmful to aquatic life [Hazardous to the aquatic environment (acute) - Category 3]GHS - JapanGovernment of Japan
Direct Hazard » Long-Term Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H412 - Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 3]GHS - JapanGovernment of Japan
- H412 - Harmful to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Hazardous to the aquatic environment - chronic category 3GHS - New ZealandTe Mana Rauhī Taiao (New Zealand EPA)
What safer alternatives are available for this chemical?
Find case studies related to substitutions for this chemical in SubsPORT, the substitution support portal.
How am I likely to be exposed to this chemical?
Ingestion
Skin contact
Eye contact
Inhalation
How can I protect myself from exposure to this chemical in the workplace?
Handle with gloves
Safety eyeware
Protective clothing
Respirator