Stronger effect / evidence
redorangeyellowgray
Weaker effect / evidence

Hydrofluoric acid

CAS: 7664-39-3

How can this chemical affect my health?

Acute (Short Term) EffectsData sources

Toxic To Humans & Animals priority 4
Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.
Irritates The Eyes priority 4
Irritates the Eyes – Can cause irritation or serious damage to the eye.
Irritates The Skin priority 4
Irritates the Skin – Can cause irritation or serious damage to the skin.

Data sources:

Direct Hazard » Toxic to Humans & Animals

These sources refer directly to this chemical:

  • H300 - Fatal if swallowed
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • H310 - Fatal in contact with skin
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • H330 - Fatal if inhaled
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • Extremely Hazardous Substances
    Extremely Hazardous Substances - EPCRA Section 302
    US Environmental Protection Agency (US EPA)
  • H300 - Fatal if swallowed
    Australia - GHS
    Safe Work Australia
  • H310 - Fatal in contact with skin
    Australia - GHS
    Safe Work Australia
  • H330 - Fatal if inhaled
    Australia - GHS
    Safe Work Australia
  • Acute toxicity (dermal) - Category 1 [H310 - Fatal in contact with skin]
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • Acute toxicity (inhalation) - Category 2 [H330 - Fatal if inhaled]
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • H300 - Fatal if swallowed
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • H310 - Fatal in contact with skin
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • H330 - Fatal if inhaled
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • 6.1A (dermal) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1A (inhalation) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1A (oral) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1B (dermal) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1B (inhalation) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1B (oral) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • Class D1A - Very toxic material causing immediate and serious toxic effects
    WHMIS-SIMDUT: Controlled Products Classifications
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
  • Acute toxicity (inhalation: gas) - Category 3
    Japan GHS Classifications
    Government of Japan
  • 6.1C (dermal) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1C (inhalation) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1C (oral) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1D (dermal) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1D (inhalation) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1D (oral) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1E (dermal) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.1E (oral) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • Class D1B - Toxic material causing immediate and serious toxic effects
    WHMIS-SIMDUT: Controlled Products Classifications
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
  • FIFRA Registered Pesticide
    Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) Registered Pesticides (Selections)
    US Environmental Protection Agency (US EPA)

Direct Hazard » Irritates the Eyes

These sources refer directly to this chemical:

  • Serious eye damage / eye irritation - Category 1
    Japan GHS Classifications
    Government of Japan
  • H318 - Causes serious eye damage
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • 8.3A - Corrosive to ocular tissue (Cat. 1)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.4A - Irritating to the eye (Cat. 2A)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Irritates the Skin

These sources refer directly to this chemical:

  • H314 - Causes severe skin burns and eye damage
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • H314 - Causes severe skin burns and eye damage
    Australia - GHS
    Safe Work Australia
  • Skin corrosion / irritation - Category 1
    Japan GHS Classifications
    Government of Japan
  • Skin corrosion/irritation - Category 1 [H314 - Causes severe skin burns and eye damage]
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • H314 - Causes severe skin burns and eye damage
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • 8.2A - Corrosive to dermal tissue (Cat. 1A)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 8.2B - Corrosive to dermal tissue (Cat. 1B)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 8.2C - Corrosive to dermal tissue (Cat. 1C)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.3A - Irritating to the skin (Cat. 2)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.3B - Mildly irritating to the skin
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

Chronic (Long Term) EffectsData sources

Birth Defects priority 3
Birth Defects – Can cause harm to the developing child including birth defects, low birth weight and biological or behavioral problems that appear as the child grows.
Other Health Effects priority 3
Other Health Effects – Can cause serious damage on contact or ingestion.
Brain/nervous System Harm priority 7
Brain/Nervous System Harm – Can cause damage to the nervous system including the brain.

Data sources:

Direct Hazard » Birth Defects

These sources refer directly to this chemical:

  • Pregnancy Risk Group C
    List of Substances with MAK & BAT Values & Categories
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)

Direct Hazard » Other Health Effects

These sources refer directly to this chemical:

  • Specific target organs/systemic toxicity following single exposure - Category 1
    Japan GHS Classifications
    Government of Japan
  • 6.9A (inhalation) - Toxic to human target organs or systems (Cat. 1)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 6.9A (oral) - Toxic to human target organs or systems (Cat. 1)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • Specific target organs/systemic toxicity following repeated exposure - Category 1
    Japan GHS Classifications
    Government of Japan

Direct Hazard » Brain/Nervous System Harm

These sources refer directly to this chemical:

  • Neurotoxic
    Chemicals with occupational exposure standards based on nervous system effects (Boyes 2001)
    Pattys Toxicology: author William K Boyes

Fluoride Compounds, Inorganic » Brain/Nervous System Harm

These sources refer to a group of compounds containing this chemical:

  • Neurotoxic
    Developmental neurotoxicity of industrial chemicals, List of 201 Chemicals known to be neurotoxic in man
    Lancet: authors Philippe Grandjean & Phil Landrigan

Inherent HazardsData sources

Reactive priority 4
Reactive – May spontaneously ignite or explode on its own or in contact with water.
Restricted List priority 5
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Data sources:

Direct Hazard » Reactive

These sources refer directly to this chemical:

  • H290 - May be corrosive to metals
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • 8.1A - Corrosive to metals
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • Class E - Corrosive materials
    WHMIS-SIMDUT: Controlled Products Classifications
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))

Direct Hazard » Restricted List

These sources refer directly to this chemical:

  • Candidate Chemical List
    Safer Consumer Product Candidate Chemicals
    California Department of Toxic Substance Control (CA DTSC)
  • Prohibited in Cosmetic Products
    EU - Cosmetics Regulation Annex II
    European Union / European Commission (EU EC)
  • Ingredients that are Prohibited for Use in Cosmetic Products
    Health Canada - Cosmetic Ingredient Hotlist
    Health Canada
  • Chemicals of High Concern
    Minnesota Department of Health - Chemicals of High Concern and Priority Chemicals
    Minnesota Department of Public Health
  • HAPs subject to the Clean Air Act
    Clean Air Act Amendments of 1990 List of Hazardous Air Pollutants
    US Environmental Protection Agency (US EPA)

How does this chemical impact the environment?Data sources

Persistent priority 2
Persistent – Does not break down readily from natural processes.
Harmful To Land Ecosystems priority 4
Harmful to Land Ecosystems – Can cause harm to land based plants, animals or microorganisms.
Immediate Harm To Aquatic Ecosystems priority 4
Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.

Data sources:

Direct Hazard » Persistent

These sources refer directly to this chemical:

  • Persistent
    Canadian Environmental Protection Act (CEPA) - Environmental Registry - Domestic Substances List (DSL)
    Environment Canada & Health Canada (EC)

Direct Hazard » Harmful to Land Ecosystems

These sources refer directly to this chemical:

  • 9.3A - Very ecotoxic to terrestrial vertebrates
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 9.3B - Ecotoxic to terrestrial vertebrates
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Immediate Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • Hazardous to the aquatic environment (acute) - Category 3
    Japan GHS Classifications
    Government of Japan
  • 9.1D (algal) - Slightly harmful in the aquatic environment or are otherwise designed for biocidal action
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 9.1D (crustacean) - Slightly harmful in the aquatic environment or are otherwise designed for biocidal action
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 9.1D (fish) - Slightly harmful in the aquatic environment or are otherwise designed for biocidal action
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

What safer alternatives are available for this chemical?

Find case studies related to substitutions for this chemical in SubsPORT, the substitution support portal.

How am I likely to be exposed to this chemical?

Fatal if swallowed
Ingestion
Fatal in contact with skin
Skin contact
Fatal if inhaled
Inhalation

How can I protect myself from exposure to this chemical in the workplace?

suit
Protective clothing
gloves
Handle with gloves
respirator
Respirator